The Biomedical Genomics Research Group was established in 2006 and is one of nine Recognised Research Groups within the Biomedical Sciences Research Institute of the University of Ulster.

The group has active research collaborations with the Systems Biology Research Group. Genomics, proteomics and Systems Biology are strongly interrelated and many complex biological and biomedical questions demand an integration of these approaches. The group has extensive expertise in key molecular biology based techniques (SNP, methylation, microarray, gene knockout), proteomic techniques (QTOF MS based de novo protein sequencing, MALDI, Yeast-2-hybrid, 2-D PAGE), and data integration and modelling (Systems Biology).

The group cover all major aspects of transcriptional control including:
 the investigation of basic mechanisms of gene regulation,
 the investigation of the structural basis for mechanisms of transcriptional control.
 the design of nucleic acid based composits to therapeutically modulate aberrant gene expression patterns.
 the analysis of the interplay of disease and a major class of transcriptional regulators (the "superfamily" of nuclear hormone receptors with a specific focus on the vitamin D receptor).
 the analysis of the correlation between genetic variability (SNPs), gene expression, promoter methylation status and specific diseases.

The pathway of breast cancer invasion of ECM

We work accross all research areas within the Biomedical Sciences Research Institute and in particular with the System Biology Research Group

Venomic research and peptide drug discovery is carried out in collaboration the University of Fuzhou, Peoples Republic of China and with Dr Stephen McClean.

State of the art core facilities and technologies available to the Group